A group of young filmmakers, led by neophyte producer Alex Romero, venture out on a location scout in rural Pennsylvania. Deep into the back country, they stumble onto a family of werewolves and must now survive the night.

A group of young adults, trying to enjoy a high school reunion party, are terrorized by an escaped mental patient obsessed with satisfying his blood lust. One by one they are made victims of the sadistic killer.