His marriage crumbling, Nick comes home one day to find his wife has vanished. And as the police turn up the heat, shocking truths come to light.

Dr. Martin Blake, who has spent his life looking for respect, meets an 18-year-old patient named Diane, suffering from a kidney infection, and gets a much-needed boost of self-esteem. However, when her health starts improving, Martin fears losing her, so he begins tampering with her treatment, keeping Diane sick and in the hospital right next to him.