For an attorney who despises losing to men and an A-list actor who distrusts women, love means nothing — until they're forced to date each other.

Song Geurim is a radio program writer who isn't exactly talented in writing. She's got the passion, initiative, and drive, but due to her lack of writing skills, she still remains an assistant writer. When she was young, the radio was the only thing in the world that she could share with her blind mother. She was consoled by the sounds of the radio and loved it more than anything, so she became a writer. When her radio program is on the verge of cancellation, she succeeds in casting a top actor Ji Suho, who can't do anything without a script.

The essence of love is fading and is evermore harder to do. In this day and age, will there be love that is woeful and forlorn just for the sake of love itself? Love in Sadness is a love story that encapsulates the mythical-like fate of love that is so coveted that it ignores all bounds. In it, love outweighs what the world thinks, ignores the pain and anguish with it, and pursues its destiny. In the drama, Ma Ri is a beautiful girl, married into wealth with a seemingly perfect life. Ironically, her husband, In Wook, who looks like a more than ideal husband, is an obsessive lunatic who is also violently abusive. When he pushes her too far, she reaches out for help from Jung Won, an honest, smart, handsome plastic surgeon. And when he agrees to help her escape from her husband's hands, they fall in love. But In Wook, who is consumed by his obsession for her, isn't going to let her get away from his grasp. Watch as these two characters struggle to stay on their arduous road to love.

It is a love story of Han Se-gye (Seo Hyun-jin) who is an A-list actress. She is known as a troublemaker and the object of many rumors. Her life is a mystery, but, in reality, she suffers from an unusual phenomenon. At a certain point every month, her appearance changes to a different person. She lives one week out of every month with a different appearance, and Seo Do-jae (Lee Min-ki) who is an executive director of an airline company. He seems perfect with an attractive appearance and intelligence but, he suffers from prosopagnosia. He hides this disability and tries hard to memorize people by their habits and mannerisms. The only face that he is able to recognize is Han Se-gye’s.

Nam Se-Hee is a single man in his early 30's. He has chosen to not marry. He owns his home, but he owes a lot on his mortgage. Yoon Ji-Ho is a single woman in her early 30's. She does not own a home and envies those that do. She has given up on dating due to her financial struggles. Yoon Ji-Ho begins to live at Nam Se-Hee’s house. They become housemates.

Can you actually not show what your true colors are while working with a lot of people? Eun Hwan Ki, the director of the top public relations agency, is a mysterious man known as “The Silent Monster.” No one knows much about him because he always avoids eye contact and appears coldly aloof and arrogant, but in truth he’s an extreme introvert — a PR executive who hates attention and is too shy to be around people. Chae Ro Woon begins to work at Eun Hwan Ki’s company. She is very energetic, the extroverted type and receives recognition for her work, but her only interest is in CEO Eun Hwan Ki. She plans to reveal who Eun Hwan-Ki really is.

When Jo Yang Sun is driven out of house and home after her father is framed for a crime, she is forced to crossdress in order to make ends meet as a bookseller, where she meets Kim Sung Yeol, a handsome, but mysterious scholar who is actually a vampire. Meanwhile, an evil presence at the royal palace stops at nothing to keep the Crown Prince from claiming his rightful throne.